Phosphopantetheine attachment site
WebACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process Alternate IDs None Definition Binding an acyl group and presenting it for processing or offloading to a cognate enzyme. Covalently binds the acyl group via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme ... WebDownload scientific diagram Phylogenetic analysis of CARs. A) Domain organization of CAR sequences: adenylation domain (PFam PF00501), phosphopantetheine (PP) …
Phosphopantetheine attachment site
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WebThe human NDUFAB1 protein contains a phosphopantetheine attachment site (DLGLDSLDQVEIIMAM), unique for acyl carrier proteins, and an EF-hand calcium binding domain (DIDAEKLMCPQEI). Transcripts of this gene are found in …
Webthis effect was dependent upon an intact phosphopantetheine attachment site (PPAS) motif within the α/β hydrolase fold of NDRG1. Materials and Methods. Cell lines and culture. BeWo, JEG-3, CHO, and NIH3T3 lines were purchased from ATCC (Manassas, VA) and cultured as we previously detailed [38-41]. We also previously characterized and detailed the Webphosphopantetheine (or pantetheine 4' phosphate) (Ppant) prosthetic group that is covalently attached to an invariant serine residue of the CP domain. CP domains, typically consisting of 70-100 residues, are either freestanding or embedded in these multifunctional proteins and exist as three variants: an
WebThe bond was not formed in a point mutant lacking the phosphopantetheine attachment site. Competition experiments with various amino acids indicated that the reaction was … WebOct 1, 2024 · Genome sequencing, comparative genomic analysis, and gene disruption of Streptomycessp. SYP-A7193 showed that the inthomycin biosynthetic gene cluster (itm) belonged to the hybrid polyketide synthase (PKS)/nonribosomal peptide …
WebMar 21, 2024 · This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ( [ACP]) domain. ( FAS_HUMAN,P49327 ) (Microbial infection) Fatty acid synthetase activity is required for SARS coronavirus-2/SARS-CoV-2 replication. ( FAS_HUMAN,P49327 )
http://amigo.geneontology.org/amigo/term/GO:0000036 list of apostles in the gospel of johnhttp://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00823 images of mokoia islandWebAug 16, 2024 · Most chemical modifications made to proteins within cells occur after the protein is synthesized in a process called translation. The resulting chemical changes are … list of apostles in matthewWebDefinition: Interacting selectively and non-covalently with the attachment site of the phosphopantetheine prosthetic group of an acyl carrier protein (ACP) as part of the process of fatty acid biosynthesis. ID: GO:0000036 Synonyms: Articles referencing this term. Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork ... images of molded case circuit breakersWebSep 2, 2014 · There is a phosphopantetheine attachment site spanning residues G 143 to M 164 in AhDGAT1-1 (G 157 to M 178 in AhDGAT1-2). A putative thiolase acyl-enzyme intermediate binding motif, previously cited in the Arabidopsis sequence by Zou et al. (1999) , is also found in AhDGAT1. It contains an invariant Pro208 at the N-terminus of this motif … list of apostles in scripturehttp://amigo.geneontology.org/amigo/term/GO:0000036 images of molasWebPhosphopantetheine attachment site Phosphopantetheine (or pantetheine 4' phosphate) is the prosthetic group of acyl carrier proteins (ACP) in some multienzyme complexes where … images of mold on marijuana plants