Gm130 molecular weight
WebIntroduction. Parkinson’s disease is the second most common neurodegenerative disease and is characterized by bradykinesia, resting tremor, rigidity and postural instability. 1,2 The loss of dopaminergic neurons in the substantia nigra pars compacta and the accumulation of α-synuclein forming Lewy bodies are the neuropathological hallmark of Parkinson’s … WebEmerging evidence suggests that GM130 is involved in the control of glycosylation, cell cycle progression, and higher order cell functions such as cell polarization and directed cell migration. This creates the potential for novel Golgi-targeted drugs and treatments for various diseases including glycosylation defects, immune diseases, and cancer.
Gm130 molecular weight
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WebNov 28, 2007 · The Golgi apparatus (GA) of mammalian cells is positioned in the vicinity of the centrosome, the major microtubule organizing center of the cell. The significance of this physical proximity for organelle function … WebApr 1, 2001 · The sequence data of the human GM130 cDNA have been submitted to DDBJ/EMBL/GenBank under accession No. AF248953. Human GM130 is a 990 aa …
WebApr 13, 2024 · a Molecular design of NGFR-EGFR-FRB 10 and NGFR-Erbb2–FKBP 9 chimeras heterodimerized by AP21967 (AP). MCF10A-5E cells 20 were serially transduced–subcloned to generate B2B1 cells. WebJul 22, 2024 · Here, we examined molecular and functional analyses of choline transporters in human pancreatic-cancer cell line MIA PaCa-2 and the elucidation of the action mechanism behind the antitumor effect of novel choline-transporter-like protein 1 (CTL1) inhibitors, Amb4269951 and its derivative Amb4269675.
WebOct 28, 2024 · GM130 plays an important role in the development of the nervous system, but the studies on it are limited. This article reviewed the current research progress of … WebHeLa cells (ATCC CCL-2) were cultured, fixed, permeabilized with Triton™ X-100, stained with Alexa Fluor® 488 Mouse anti-GM130 (pseudo colored green), and counter stained with Hoechst 33342 (pseudo colored blue) according to the Recommended Assay Procedure. The images were captured on a BD Pathway™ 435 Cell Analyzer with a 20x objective ...
WebMonoclonal Antibody for studying GM130. Cited in 132 publications. Validated for WB, IP, IF. Available in 2 sizes. Highly specific and …
WebGM130 is part of a cis-Golgi matrix and has a role in maintaining cis-Golgi structure. T HE Golgi apparatus receives the entire output of newly-synthesized proteins from the ER. ... and a molecular weight in excess of 350 kD (Linstedt and Hauri, 1993; Seelig et al., 1994; Sohda et al., 1994). Unlike eating moneyWebMay 2, 1997 · The lower molecular weight protein recognized by anti-p115 antibodies (Figure 2B, lane 6) is a proteolytic fragment that weakly binds to GM130 (Figure 2B, lane 9). No binding was observed using lysates from bacteria expressing the vector alone (data not shown). The N-Terminus of GM130 Binds p115 compact shrubs for front yardWebJun 15, 1998 · We have shown previously that GRASP65 and GM130 can be co-immunoprecipitated from a detergent extract of purified rat liver Golgi membranes, and that both GRASP65 and GM130 are present in high molecular weight fractions by gel filtration, indicating that they may be part of the same large complex (Nakamura et al., 1995; Barr … compact single strollerWebGM130 is proposed to function as a membrane skeleton, maintaining the structure of the Golgi apparatus, and as a vesicle tether that facilitates vesicle fusion to the Golgi … compact sink sizeseating money meaningWebCalculated molecular weight: 111 kDa: GenBank accession number: BC014188: Gene symbol: GOLGA2: Gene ID (NCBI) 2801: Conjugate: CoraLite®594 Fluorescent Dye: ... GOLGA2, also known as GM130, is a … compact size synonymWebDec 27, 2016 · Although the Golgi apparatus is well characterized at the molecular level, its roles in development and in tissue homeostasis, and how its dysfunction contributes to … eating monkey brains scene