Chromomycin-a3

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August undefined, 2024

Web丁香通为您找到694条(+)-打碗花精 a3厂家的工商注册年份、员工人数、年营业额、信用记录、主营产品、相关(+)-打碗花精 a3产品的供求信息、交易记录等企业详情。丁香通为买家提供用户服务，诚信保障等服务，批发采购(+)-打碗花精 a3，上丁香通。 WebThe biosynthetic gene cluster of the aureolic acid type antitumor drug chromomycin A3 from S. griseus subsp. griseus has been identified and characterized. It spans 43 kb and …

Chromomycin A2 induces autophagy in melanoma cells - PubMed

WebApr 27, 2024 · Chromomycin A3 (which is interesting also an antibiotic!), which binds to GC-rich regions of DNA. A Hoechst stain (e.g. 33258 or 33342), that binds to AT-rich regions. Using these DNA stains, we can separate the larger chromosomes from the smaller ones as they will contain more DNA and will thus yield a greater fluorescence signal. Chromomycin A3 (CMA3) or Toyomycin is an anthraquinone antibiotic glycoside produced by the fermentation of a certain strain of Streptomyces griseus (No. 7). See more In the presence of Mg ions, Chromomycin A3 binds reversibly to DNA, preferentially to contiguous G/C base pairs. When bound to DNA, Chromomycin A3 has a maximum excitation wavelength of 445 See more • in-vitro membrane-impermeant G/C-specific fluorescent DNA-binding dye. • in-vitro antibiotic of gram-positive bacteria, through inhibition of the incorporation of Pi in the RNA. • in-vitro anticancer drug that inhibits RNA synthesis. See more dutch mountain house

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WebChromomycin A 3 is a GC-specific DNA ligand which inhibits transcription. It may be used as a fluorescent DNA stain. Antibiotic. Cell permeable fluorescent dye that cann be used … WebChromomycin a3 C57H82O26 CID 656673 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. WebChromomycin A3 is an antibiotic that binds to the GC-rich sequence of DNA in the presence of divalent cations, inhibiting DNA replication and transcription (1). It is also used as a … dutch mountains tent

NMR studies of the interaction of chromomycin A3 with small …

R显带 - 维基百科，自由的百科全书

WebChromomycin A3 (CMA3) Protamination state of the spermatozoa determines its chromatin integrity status. The lesser the protamine content, the poorer the DNA packaging and the higher the sperm DNA damage. CMA3 binds to the sperm DNA deficient of protamine and stains light yellow [74]. The intensity of color is high in sperm with increased prot ... Web#: ALX-380-055 Chromomycin A 3 is a GC-specific DNA ligand which inhibits transcription. It may be used as a fluorescent DNA stain. Antibiotic. Cell permeable fluorescent dye that cann be used with Bisbenzimide H33258 to distinguish chromosomes by their total DNA concentration and their DNA base composition. Does not intercalate. cryptshare anleitungWebChromomycin A3 as a fluorescent probe for flow cytometry of human gynecologic samples Author R H Jensen PMID: 70448 DOI: 10.1177/25.7.70448 Abstract Chemical, physical and optical properties of chromomycin A3 are examined so as to ascertain appropriate staining and analysis procedures for flow cytometry of human gynecologic samples. cryptshare aok

"WebChromomycin A3 and mithramycin are antibiotics binding preferentially to the GC-rich regions of DNA. They have excitation maxima at 440 nm and emission maxima at 555 and 575 nm, respectively. Unfortunately the low fluorescence intensity … " - Chromomycin-a3

Chromomycin-a3

WebJun 7, 2024 · The Chromomycin A3 (CMA3) and Acridine orange (AO) staining were performed to examine the sperm DNA fragmentation status. CCl4 treatment showed a significant decrease in antioxidant markers and sperm count, viability, normal morphology and motility as well as significantly increased the testicular oxidative stress markers, and … http://www.cyto.purdue.edu/cdroms/cyto10a/sponsors/media/dako/mofloxdp/chromosome.pdf

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WebDec 4, 2014 · The present study highlights the biological effects of chromomycin A2 toward metastatic melanoma cells in culture. Besides chromomycin A2, chromomycin A3 and demethylchromomycin A2 were also identified from the extract derived from Streptomyces sp., recovered from Paracuru Beach, located in the northeast region of Brazil. The … Web其显示的人类染色体带型与Q带或G带相反，异染色质区如染色体的，一般在Q带或G显带中深染，常染色质区浅染，而R带则异染色质区一般浅染，常染色质区深染。. 其他R显带的方法包括用chromomycin A3或olivomycin等荧光素染色，或在细胞周期的合成期（S期）将 ...

WebApr 6, 2024 · Chromomycin A3 (CMA3, Figure 17.1) is an antibiotic glycoside produced by the fermentation of a certain strain of Streptomyces griseous. In the presence of bivalent … WebThis article is cited by 34 publications. Sangita Majee,, Ranjan Sen,, Suranjana Guha,, Dhananjay Bhattacharyya, and, Dipak Dasgupta. Differential Interactions of the Mg2+ Complexes of Chromomycin A3 and Mithramycin with Poly(dG-dC)·Poly(dC-dG) and Poly(dG)·Poly(dC).

WebJan 14, 2024 · Description. Chromomycin A3 is an aureolic acid-type antitumor antibiotic. Chromomycin A3 forms dimeric complexes with divalent cations, such as Mg2+, which strongly binds to the GC rich sequence of DNA to inhibit DNA replication and transcription. Chromomycin A3 has a variety of utilities as a staining agent for human sperm … WebFeb 25, 1997 · The interaction of the two anticancer antibiotics, chromomycin A 3 and mithramycin, with the polynucleotides poly (dG-dC).poly (dC-dG), representative of B-DNA, and poly (dG)·poly (dC), representative of A-DNA, in the presence of Mg 2+ is studied by spectroscopic techniques such as absorbance, fluorescence, and dircular dichroism (CD).

WebNov 19, 1985 · The binding of chromomycin A3 to calf thymus DNA and poly (dG-dC) has been studied by 13C and 1H NMR with emphasis on the mode of binding, the role of Mg2+, and pH effects.

WebChromomycin A3 from Streptomyces griseus is an antibiotic exhibiting anti-bacterial, anti-fungal and antitumor activities. [ 3] It serves as a fluorescent DNA stain. [ 4] It is useful for the detection of protamine deficiency in sperm chromatin. dutch mounted bicycle bandWebApplication: Chromomycin A3 is a G-C specific DNA ligand which inhibits transcription and acts as a DNA binding dye CAS Number: 7059-24-7 Purity: ≥97% Molecular Weight: 1183.25 Molecular Formula: C 57 H 82 … dutch movement \u0026 feestdjruud - turn the tideWebJun 2, 2024 · protamine deficiency by chromomycin A3 (CMA3) staining. In addition, the relationship between the fertilisation rate and sperm ubiquitination was calculated in ICSI candidates. The intensity of ubiquitination showed a significant negative correlation with sperm concentration (r = 0.255, P = 0.032) and a cryptshare apeldoornWebChromomycin A3 445 575 CyTRAK Orange™* 457,488,549 615 Ethidium Bromide 493 620 Propidium iodide (PI) 305,540 620 325,360,488 DRAQ5™ 646 681,697 DRAQ7™ 599, 644 678,697 Single dye F ora singl efu c t dy, hx w vp electromagnetic energy to an electron in that molecule (1). The electron moves to an excitation state at the next energy level ... cryptshare apiWebFeb 1, 1974 · Chromomycin A3 shows potent antitumor activity against several experimental tumor systems, including Ehrlich carcinoma, Yoshida sarcoma, sarcoma 180, leukemia SN 36 (Tatsuoka et al., 1958), and lymphoid leukemia L1210 and P388 (National Cancer Institute, 1968). dutch moversWeb(Hoechst 33258, Chromomycin A3). Highly purified fractions of chromosomes can then be isolated rapidly from the labeled chromosomes using the MoFlo High performance Cell Sorter. Chromosome preparation and staining. Block cells at metaphase using 0.1 µg/ml demecolcine for an optimized amount of time to maximize the percentage of mitotic cells cryptshare anmeldungWebIn-Person Course Schedule - Industrial Refrigeration …. 1 week ago Web Ends: Apr 21st 2024 5:00PM. Fee: $1,225.00. Register By: Apr 17th 2024 2:17PM. Collapse. This is a … cryptshare assen